Chemical & Physical Properties
- Appearance: White to grayish crystalline powder
- Melting Point: ~125–150°C (Decomposes)
- Solubility: Reacts violently with water, releasing deuterium gas (D₂)
- Reactivity: Strong reducing agent, decomposes in air and moisture
- Stability: Stable under dry, inert conditions
Key Features & Benefits
✅ Deuterium-Enriched Reducing Agent: Facilitates selective reduction in deuterium labeling
✅ Essential for Deuterated Compound Synthesis: Used in pharmaceuticals, NMR studies, and isotopic research
✅ High Reactivity & Efficiency: Enables efficient reduction of carbonyl and imine functional groups
✅ Anhydrous & Ultra-Pure Options Available: Suitable for high-sensitivity applications
Industrial & Laboratory Applications
Organic & Pharmaceutical Synthesis
- Deuterium Labeling:
- Used to introduce deuterium (D) into organic molecules for pharmaceutical and biochemical studies.
- Reduction Reactions:
- Reduces esters, carboxylic acids, ketones, and aldehydes to their corresponding alcohols.
Isotope Chemistry & Spectroscopy
- NMR & Mass Spectrometry Studies:
- Used for preparing deuterium-labeled standards in structural analysis.
- Hydrogen-Deuterium Exchange Reactions:
- Facilitates isotopic substitution for kinetic and mechanistic studies.
Materials Science & Energy Research
- Hydrogen Storage Research:
- Investigated for potential applications in hydrogen isotope storage and fuel cell technology.
Handling & Safety Considerations
⚠️ Highly Reactive & Pyrophoric!
- Water Sensitivity: Reacts violently with water, releasing flammable deuterium gas (D₂).
- Air Sensitivity: Decomposes upon exposure to air, producing lithium hydroxide and aluminum hydroxide.
- Handling Precautions:
- Use only in dry, inert atmospheres (glovebox or Schlenk techniques).
- Avoid contact with moisture, acids, and oxidizers.
Storage & Packaging
- Storage Conditions:
- Store in sealed, moisture-proof containers under an inert gas (argon or nitrogen).
- Keep in a cool, dry environment away from ignition sources.
- Personal Protective Equipment (PPE):
- Use gloves, protective eyewear, and flame-resistant lab coats.
- Handle in an inert gas atmosphere with explosion-proof equipment.
Available in:
- 1g, 5g, 25g, 100g, and bulk quantities
- Custom purities available upon request
Lithium Aluminium Deuteride (LiAlD₄) is a deuterated analog of lithium aluminium hydride (LiAlH₄), widely used as a selective reducing agent in organic synthesis. It plays a crucial role in the production of deuterated compounds, which are essential in pharmaceutical research, isotopic labeling, and NMR spectroscopy. LiAlD₄ is a highly reactive and moisture-sensitive solid, requiring careful handling under inert conditions.