Date: 2026-05-16
Why Boron Tribromide Is Widely Used for Demethylation in Pharmaceutical Synthesis
Boron Tribromide (BBr3) is one of the most widely used demethylation reagents in modern organic synthesis. Thanks to its strong Lewis acidity and excellent selectivity, it is extensively applied in pharmaceutical intermediates, fine chemicals, and electronic material production.
Compared with traditional demethylation systems, BBr3 often provides cleaner reactions, better yields, and improved process control, making it a preferred choice for both laboratory and industrial-scale synthesis.
Read More
